6ATG

Insights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	HCG40889, isoform CRA_b	polymer	61	6984.1	2	UniProt (A0A024R962) Pfam (PF00084) UniProt (by SIFTS) (P08603) In PDB	Homo sapiens (Human)
2	B, C	Complement regulator-acquiring surface protein 2 (CRASP-2)	polymer	214	24679.1	2	UniProt (O50665) Pfam (PF22487) In PDB	Borrelia burgdorferi B31
3	B, C	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4		water	water		18.0	661	Chemie (HOH)

Sequence modifications

A, D: 370 - 428 (UniProt: A0A024R962)

PDB	External Database	Details
His 368	-	expression tag
Met 369	-	expression tag

B, C: 25 - 235 (UniProt: O50665)

PDB	External Database	Details
Gly 22	-	expression tag
His 23	-	expression tag
Met 24	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	63326.3
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	63374.9

*Water molecules are not included.