6ATE
SRC kinase bound to covalent inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase Src | polymer | 286 | 32710.6 | 1 | UniProt (P12931) Pfam (PF07714) | Homo sapiens (Human) | Proto-oncogene c-Src,pp60c-src,p60-Src |
| 2 | B (A) | N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | non-polymer | 466.0 | 1 | Chemie (6H3) | |||
| 3 | C (A) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A: 254 - 536 (UniProt: P12931)
| PDB | External Database | Details |
|---|---|---|
| Gly 251 | - | expression tag |
| His 252 | - | expression tag |
| Met 253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32710.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 466.0 | |
| All* | Total formula weight | 33176.6 |
