6AQS
Crystal structure of Plasmodium falciparum purine nucleoside phosphorylase (V181D) mutant complexed with DADMe-ImmG and phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Purine nucleoside phosphorylase | polymer | 246 | 26994.2 | 1 | UniProt (Q8T9Z7) Pfam (PF01048) UniProt (by SIFTS) (Q8I3X4) In PDB | Plasmodium falciparum | |
| 2 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | A | 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one | non-polymer | 279.3 | 1 | Chemie (IM5) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A: 1 - 245 (UniProt: Q8T9Z7)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Asp 181 | Val 181 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26994.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 498.4 | |
| All* | Total formula weight | 27492.6 |
