6AN1
Crystal structure of the complex between PPARgamma LBD and the ligand AM-879
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor gamma | polymer | 286 | 32622.7 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | C (A) | 4-({2-[(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)methyl]phenoxy}methyl)benzoic acid | non-polymer | 384.4 | 1 | Chemie (BKY) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A, B: 196 - 477 (UniProt: P37231)
| PDB | External Database | Details |
|---|---|---|
| Gly 192 | - | expression tag |
| Ser 193 | - | expression tag |
| His 194 | - | expression tag |
| Met 195 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65245.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 384.4 | |
| All* | Total formula weight | 65629.9 |
