6AL5

COMPLEX BETWEEN CD19 (N138Q MUTANT) AND B43 FAB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	B-lymphocyte antigen CD19	polymer	265	29302.4	1	UniProt (P15391)	Homo sapiens (Human)	B-lymphocyte surface antigen B4,Differentiation antigen CD19,T-cell surface antigen Leu-12
2	B (L)	B43 LIGHT CHAIN	polymer	218	23815.3	1	UniProt (Q6P5S8) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (Human)
3	C (H)	B43 HEAVY CHAIN	polymer	233	25225.1	1	UniProt (A8K008) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (Human)
4	D, E (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	F, G (L, H)	water	water		18.0	2	Chemie (HOH)

Sequence modifications

A: 21 - 277 (UniProt: P15391)

PDB	External Database	Details
Gln 138	Asn 138	engineered mutation
Gly 278	-	expression tag
Ser 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag
His 284	-	expression tag
His 285	-	expression tag

L: 1 - 108 (PDB: 6AL5)
L: 109 - 218 (UniProt: Q6P5S8)
H: 1 - 113 (PDB: 6AL5)
H: 114 - 227 (UniProt: A8K008)

PDB	External Database	Details
His 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag
His 231	-	expression tag
His 232	-	expression tag
His 233	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	78342.8
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	78785.2

*Water molecules are not included.