6AJE

Crystal structure of DHODH in complex with ferulenol from Eimeria tenella

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Dihydroorotate dehydrogenase (quinone), mitochondrial	polymer	436	48792.2	4	UniProt (U6KL66) Pfam (PF01180)	Eimeria tenella (Coccidian parasite)	DHOdehase
2	E, H, K, N (A, B, C, D)	FLAVIN MONONUCLEOTIDE	non-polymer		456.3	4	Chemie (FMN)
3	F, I, L, O (A, B, C, D)	OROTIC ACID	non-polymer		156.1	4	Chemie (ORO)
4	G, J, M, P (A, B, C, D)	4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one	non-polymer		366.5	4	Chemie (9AU)

Sequence modifications

A, B, C, D: 1 - 414 (UniProt: U6KL66)

PDB	External Database	Details
Met -21	-	initiating methionine
Gly -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
His -7	-	expression tag
Ile -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Lys -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	195168.7
Non-Polymers*	Number of molecules	12
	Total formula weight	3915.7
All*	Total formula weight	199084.4

*Water molecules are not included.