6AJB
Crystal structure of Trypanosoma brucei glycosomal isocitrate dehydrogenase in complex with NADH, alpha-ketoglutarate and ca2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Isocitrate dehydrogenase [NADP] | polymer | 413 | 46791.6 | 4 | UniProt (Q387G0) Pfam (PF00180) In PDB | Trypanosoma brucei brucei | |
| 2 | A, B, C, D | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | A, B, C, D | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | D | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) |
Sequence modifications
A, B, C, D: 1 - 413 (UniProt: Q387G0)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | Met 1 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 187166.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2960.1 | |
| All* | Total formula weight | 190126.5 |
