6AH5

Structure of human P2X3 receptor in complex with ATP and Mg2+ ion

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	P2X purinoceptor 3	polymer	362	40793.0	3	UniProt (P56373) Pfam (PF00864)	Homo sapiens (Human)	P2X3,ATP receptor,Purinergic receptor
2	D, E, F (D, E, F)	alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose	branched		342.3	3	In PDB BIRD (PRD_900001) GlyTouCan (G07411ON)		alpha-maltose
3	G, K, Q (A, B)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	3	Chemie (ATP)
4	H, I, M, N, O... (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
5	J, P, V (A, B, C)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
6	L, R, W (A, B, C)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)

Sequence modifications

A, B, C: 17 - 363 (UniProt: P56373)

PDB	External Database	Details
Ser 2	-	expression tag
Arg 3	-	expression tag
Glu 4	-	expression tag
Phe 5	-	expression tag
Asp 6	-	expression tag
Phe 7	-	expression tag
Phe 8	-	expression tag
Thr 9	-	expression tag
Tyr 10	-	expression tag
Glu 11	-	expression tag
Thr 12	-	expression tag
Pro 13	-	expression tag
Lys 14	-	expression tag
Val 15	-	expression tag
Ile 16	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	122378.9
Branched	Number of molecules	3
	Total formula weight	1026.9
Non-Polymers*	Number of molecules	17
	Total formula weight	3550.3
All*	Total formula weight	126956.1

*Water molecules are not included.