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6AFY

Proton pyrophosphatase-E225S mutant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Pyrophosphate-energized vacuolar membrane proton pumppolymer76680050.82UniProt (P21616)
Pfam (PF03030)
Vigna radiata var. radiata (Mung bean)Pyrophosphate-energized inorganic pyrophosphatase,H(+)-PPase,Vacuolar H(+)-pyrophosphatase
2C, D, O, P
(A, B)
PHOSPHATE IONnon-polymer95.04Chemie (PO4)
3E, F, G, H, I...
(A, B)
MAGNESIUM IONnon-polymer24.310Chemie (MG)
4J, V
(A, B)
POTASSIUM IONnon-polymer39.12Chemie (K)
5K, L, M, N, W...
(A, B)
2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOLnon-polymer252.36Chemie (1PG)
6Y, Z
(A, B)
waterwater18.0361Chemie (HOH)
Sequence modifications
A, B: 1 - 766 (UniProt: P21616)
PDBExternal DatabaseDetails
Ser 225Glu 225engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight160101.6
Non-Polymers*Number of molecules22
Total formula weight2215.0
All*Total formula weight162316.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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