6AEK
Crystal structure of ENPP1 in complex with pApG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ectonucleotide pyrophosphatase/phosphodiesterase 1, isoform CRA_d | polymer | 738 | 84816.2 | 1 | UniProt (G3X9S2) Pfam (PF01663) Pfam (PF01223) UniProt (by SIFTS) (P06802) | Mus musculus (Mouse) | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
| 2 | B (B) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 3 | C, D, E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 4 | F (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 5 | G (A) | GUANOSINE-5'-MONOPHOSPHATE | non-polymer | 363.2 | 1 | Chemie (5GP) | |||
| 6 | H, I (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 7 | J (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 8 | K, L, M, N, O... (A) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 9 | Q, R, S, T, U... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 10 | W (A) | water | water | 18.0 | 322 | Chemie (HOH) |
Sequence modifications
A: 170 - 905 (UniProt: G3X9S2)
| PDB | External Database | Details |
|---|---|---|
| Gly 168 | - | See sequence details |
| Pro 169 | - | See sequence details |
| Ala 238 | Thr 238 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 84816.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2130.1 | |
| All* | Total formula weight | 87532.8 |
