6AEE

Crystal structure of the four Ig-like domains of LILRB1 complexed with HLA-G

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	HLA class I histocompatibility antigen, alpha chain G	polymer	277	32046.6	2	UniProt (P17693) Pfam (PF00129) Pfam (PF07654) In PDB	Homo sapiens (Human)	HLA G antigen,MHC class I antigen G
2	B, E	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	C, F	9 Mer Peptide (RL9) From Histone H2A.x	polymer	9	1148.4	2	UniProt (by SIFTS) (P04908) In PDB	Homo sapiens
4	G, H	Leukocyte immunoglobulin-like receptor subfamily B member 1	polymer	399	44143.1	2	UniProt (A0A0G2JQ44) Pfam (PF13895) Pfam (PF00047) UniProt (by SIFTS) (Q8NHL6) In PDB	Homo sapiens (Human)

Sequence modifications

A, D: 1 - 276 (UniProt: P17693)

PDB	External Database	Details
Met 0	-	initiating methionine
Ser 42	Cys 66	engineered mutation
Ile 110	Leu 134	engineered mutation
Arg 115	Gln 139	engineered mutation

B, E: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 1	-	initiating methionine

G, H: 2 - 394 (UniProt: A0A0G2JQ44)

PDB	External Database	Details
His 395	-	expression tag
His 396	-	expression tag
His 397	-	expression tag
His 398	-	expression tag
His 399	-	expression tag
His 400	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	178435.0
All*	Total formula weight	178435.0

*Water molecules are not included.