6ADY

Crystal structure of the Zika virus NS3 helicase (ADP-Mn2+ complex, form 2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Serine protease NS3	polymer	448	50412.6	1	UniProt (Q32ZE1) Pfam (PF07652) Pfam (PF20907) In PDB	Zika virus (strain Mr 766) (ZIKV)
2	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
3	A	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
4		water	water		18.0	271	Chemie (HOH)

Sequence modifications

A: 181 - 617 (UniProt: Q32ZE1)

PDB	External Database	Details
Met 170	-	expression tag
His 171	-	expression tag
His 172	-	expression tag
His 173	-	expression tag
His 174	-	expression tag
His 175	-	expression tag
His 176	-	expression tag
Ser 177	-	expression tag
Ser 178	-	expression tag
Ser 179	-	expression tag
Gly 180	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	50412.6
Non-Polymers*	Number of molecules	2
	Total formula weight	482.1
All*	Total formula weight	50894.7

*Water molecules are not included.