6AD3

Structural characterization of the condensation domain from Monacolin K polyketide synthase MokA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Lovastatin nonaketide synthase mokA	polymer	519	57446.2	1	UniProt (Q3S2T9) Pfam (PF00668)	Monascus pilosus (Red mold)	Monacolin K biosynthesis protein A
2	B (A)	water	water		18.0	260	Chemie (HOH)

Sequence modifications

A: 2 - 499 (UniProt: Q3S2T9)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Met 1	-	expression tag
Trp 153	Arg 2729	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	57446.2
All*	Total formula weight	57446.2

*Water molecules are not included.