6AAH

Crystal structure of JAK1 in complex with peficitinib

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tyrosine-protein kinase JAK1	polymer	290	33489.2	2	UniProt (P23458) Pfam (PF07714) In PDB	Homo sapiens (Human)	Janus kinase 1,JAK-1
2	A, B	4-[[(1S,3R)-5-oxidanyl-2-adamantyl]amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide	non-polymer		326.4	2	Chemie (9T6)
3		water	water		18.0	232	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66978.4
Non-Polymers*	Number of molecules	2
	Total formula weight	652.8
All*	Total formula weight	67631.2

*Water molecules are not included.