6AA3
Crystal structure of MTH1 in apo form (cocktail No. 1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 7,8-dihydro-8-oxoguanine triphosphatase | polymer | 163 | 18985.6 | 1 | UniProt (P36639) Pfam (PF00293) | Homo sapiens (Human) | 2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1 |
| 2 | B, C, D (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F (A) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 3 - 156 (UniProt: P36639)
| PDB | External Database | Details |
|---|---|---|
| Met 2 | - | initiating methionine |
| Leu 157 | - | expression tag |
| Glu 158 | - | expression tag |
| His 159 | - | expression tag |
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| His 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18985.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 292.3 | |
| All* | Total formula weight | 19277.9 |
