6A95
Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with tetrodotoxin and Dc1a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium channel protein PaFPC1 | polymer | 1596 | 183875.4 | 1 | UniProt (D0E0C2) | Periplaneta americana (American cockroach) | Voltage-gated sodium channel,PaFPC1,NavPaS |
| 2 | B (B) | Mu-diguetoxin-Dc1a | polymer | 57 | 6502.4 | 1 | UniProt (P49126) | Diguetia canities (Desert bush spider) | Mu-DGTX-Dc1a,Insecticidal toxin DTX9.2 |
| 3 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | E, F, G (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 5 | H (A) | (1R,5R,6R,7R,9S,11S,12S,13S,14S)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name) | non-polymer | 319.3 | 1 | Chemie (9SR) PubChem (16220031) PubChem (16759596) PubChem (17760111) PubChem (20022997) PubChem (20022999) PubChem (21733123) PubChem (20382) PubChem (22525017) PubChem (177391273) PubChem (177407504) PubChem (23451521) PubChem (23637407) PubChem (127071) PubChem (163882) PubChem (24847904) PubChem (25079217) PubChem (25200036) PubChem (443369) PubChem (20055121) PubChem (42620490) PubChem (42620491) PubChem (44519176) PubChem (44519678) PubChem (44519679) PubChem (44519680) PubChem (44602429) PubChem (45073455) PubChem (45269625) PubChem (53361420) PubChem (53361422) PubChem (3038098) PubChem (57164700) PubChem (54592379) PubChem (59509159) PubChem (4490623) PubChem (5281968) PubChem (5311477) PubChem (5460547) PubChem (6324668) PubChem (78210120) PubChem (88555915) PubChem (89357806) PubChem (6915883) PubChem (9818475) PubChem (9861836) PubChem (9892264) PubChem (11174599) PubChem (11493449) PubChem (11616707) PubChem (11886797) PubChem (11970257) PubChem (12359127) PubChem (12359128) PubChem (12359138) PubChem (98592648) PubChem (98592649) PubChem (99646209) PubChem (99646210) PubChem (99719283) PubChem (99843883) PubChem (101623282) PubChem (101642969) PubChem (124389678) PubChem (124744973) PubChem (122173180) PubChem (124525681) PubChem (124577437) PubChem (124744971) PubChem (124744972) PubChem (124842472) PubChem (124842473) PubChem (124842474) PubChem (129432425) PubChem (131676377) PubChem (132266642) PubChem (134940882) PubChem (135566033) PubChem (137545948) PubChem (137699575) PubChem (138107311) PubChem (138374192) PubChem (138962764) PubChem (139251219) PubChem (140325589) PubChem (140583337) PubChem (146028144) PubChem (146031683) PubChem (147212717) PubChem (155293189) PubChem (155540323) PubChem (155929350) PubChem (156022281) PubChem (156022364) PubChem (162945060) PubChem (162945061) PubChem (162945062) PubChem (163195019) PubChem (164669099) PubChem (168274932) PubChem (168276714) PubChem (168312527) PubChem (171035072) PubChem (171666766) PubChem (171761685) PubChem (171761689) PubChem (172013399) PubChem (175613397) | |||
| 6 | I (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 7 | J (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 1 - 1553 (UniProt: D0E0C2)
B: 2 - 57 (UniProt: P49126)
| PDB | External Database | Details |
|---|---|---|
| Met -42 | - | expression tag |
| Ala -41 | - | expression tag |
| Ser -40 | - | expression tag |
| Trp -39 | - | expression tag |
| Ser -38 | - | expression tag |
| His -37 | - | expression tag |
| Pro -36 | - | expression tag |
| Gln -35 | - | expression tag |
| Phe -34 | - | expression tag |
| Glu -33 | - | expression tag |
| Lys -32 | - | expression tag |
| Gly -31 | - | expression tag |
| Gly -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Ala -28 | - | expression tag |
| Arg -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Ser -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Gly -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Ser -20 | - | expression tag |
| Trp -19 | - | expression tag |
| Ser -18 | - | expression tag |
| His -17 | - | expression tag |
| Pro -16 | - | expression tag |
| Gln -15 | - | expression tag |
| Phe -14 | - | expression tag |
| Glu -13 | - | expression tag |
| Lys -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Phe -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Tyr -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Lys -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Thr 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 190377.9 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1005.9 | |
| All* | Total formula weight | 192232.5 |
