6A8O
Crystal structures of the serine protease domain of murine plasma kallikrein with peptide inhibitor mupain-1-16
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Plasma kallikrein | polymer | 248 | 27645.3 | 2 | UniProt (P26262) Pfam (PF00089) | Mus musculus (Mouse) | Fletcher factor,Kininogenin,Plasma prekallikrein |
| 2 | C (P) | peptide inhibitor, | polymer | 10 | 1105.2 | 1 | Synthemiopsis | ||
| 3 | D, E (A, B) | alpha-D-mannopyranose | non-polymer | 180.2 | 2 | Chemie (MAN) | |||
| 4 | F (P) | piperidine-1-carboximidamide | non-polymer | 127.2 | 1 | Chemie (MRZ) |
Sequence modifications
A, B: 16 - 255 (UniProt: P26262)
P: 1 - 6 (PDB: 6A8O)
P: 7 - 10 (PDB: 6A8O)
| PDB | External Database | Details |
|---|---|---|
| Ser 122 | Cys 503 | engineered mutation |
P: 7 - 10 (PDB: 6A8O)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 56395.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 487.5 | |
| All* | Total formula weight | 56883.3 |
