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6A7E

Human dihydrofolate reductase complexed with NADPH and BT2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADihydrofolate reductasepolymer18621349.51UniProt (P00374)
Pfam (PF00186)
In PDB
Homo sapiens (Human)
2A5-(4-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-6-ethylpyrimidine-2,4-diaminenon-polymer424.51Chemie (9QR)
3ANADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
4waterwater18.0161Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight21349.5
Non-Polymers*Number of molecules2
Total formula weight1169.9
All*Total formula weight22519.4
*Water molecules are not included.

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