6A7B
AKR1C3 complexed with new inhibitor with novel scaffold
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Aldo-keto reductase family 1 member C3 | polymer | 323 | 36906.2 | 2 | UniProt (P42330) Pfam (PF00248) In PDB | Homo sapiens (Human) | 17-beta-hydroxysteroid dehydrogenase type 5,17-beta-HSD 5,3-alpha-HSD type II,brain,3-alpha-hydroxysteroid dehydrogenase type 2,3-alpha-HSD type 2,Chlordecone reductase homolog HAKRb,Dihydrodiol dehydrogenase 3,DD3,Dihydrodiol dehydrogenase type I,HA1753,Indanol dehydrogenase,Prostaglandin F synthase,PGFS,Testosterone 17-beta-dehydrogenase 5,Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase |
| 2 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | A, B | (4R)-6-amino-4-(4-hydroxy-3-methoxy-5-nitrophenyl)-3-propyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | non-polymer | 371.3 | 2 | Chemie (9S0) | |||
| 4 | A, B | DIMETHYLFORMAMIDE | non-polymer | 73.1 | 4 | Chemie (DMF) | |||
| 5 | water | water | 18.0 | 208 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73812.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2521.9 | |
| All* | Total formula weight | 76334.3 |
