6A78
Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the scFv fragment of murine monoclonal antibody B5209B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Roundabout homolog 1 | polymer | 91 | 9776.1 | 2 | UniProt (Q9Y6N7) Pfam (PF13927) | Homo sapiens (Human) | Deleted in U twenty twenty,H-Robo-1 |
| 2 | B, E (L, M) | Light chain region of the anti-human Robo1 antibody B5209B scFv | polymer | 112 | 11999.4 | 2 | Mus musculus | ||
| 3 | C, F (H, I) | Heavy chain and linker region of the anti-human Robo1 antibody B5209B scFv | polymer | 138 | 14374.8 | 2 | Mus musculus | ||
| 4 | G, H (L, M) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | I, J, K, L, M... (A, L, H, B, M...) | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence modifications
A, B: 9 - 97 (UniProt: Q9Y6N7)
| PDB | External Database | Details |
|---|---|---|
| Met 7 | - | expression tag |
| Gly 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 72300.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 72492.7 |
