6A6M
Crystal structure of an outward-open nucleotide-bound state of the eukaryotic ABC multidrug transporter CmABCB1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP-binding cassette, sub-family B, member 1 | polymer | 612 | 66046.6 | 1 | UniProt (M1VAN7) Pfam (PF00664) Pfam (PF00005) | Cyanidioschyzon merolae strain 10D (Red alga) | |
| 2 | B (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D, E, F (A) | DECYL-BETA-D-MALTOPYRANOSIDE | non-polymer | 482.6 | 3 | Chemie (DMU) PubChem (3637526) PubChem (5288091) PubChem (24776995) PubChem (45253991) PubChem (45254001) PubChem (16396531) PubChem (24802064) PubChem (45253971) PubChem (49866911) PubChem (95370473) PubChem (98046563) PubChem (5288728) PubChem (101207920) PubChem (56845266) PubChem (126735852) PubChem (58112552) PubChem (59518661) PubChem (168490163) PubChem (70796430) PubChem (70839938) PubChem (71307274) PubChem (95370474) PubChem (95370475) PubChem (95370476) PubChem (98046559) PubChem (98046561) PubChem (100941450) PubChem (100950626) PubChem (102219024) PubChem (118704896) PubChem (123134571) PubChem (124867949) PubChem (124867950) PubChem (124867951) PubChem (124867952) PubChem (126731012) PubChem (126731036) PubChem (126735974) | |||
| 5 | G (A) | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) PubChem (943) | |||
| 6 | H (A) | water | water | 18.0 | 435 | Chemie (HOH) |
Sequence modifications
A: 93 - 696 (UniProt: M1VAN7)
| PDB | External Database | Details |
|---|---|---|
| Ala 147 | Gln 147 | engineered mutation |
| Ala 381 | Thr 381 | engineered mutation |
| Gly 697 | - | expression tag |
| Ser 698 | - | expression tag |
| Glu 699 | - | expression tag |
| Asn 700 | - | expression tag |
| Leu 701 | - | expression tag |
| Tyr 702 | - | expression tag |
| Phe 703 | - | expression tag |
| Gln 704 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66046.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2040.2 | |
| All* | Total formula weight | 68086.8 |
