6A6M
Crystal structure of an outward-open nucleotide-bound state of the eukaryotic ABC multidrug transporter CmABCB1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP-binding cassette, sub-family B, member 1 | polymer | 612 | 66046.6 | 1 | UniProt (M1VAN7) Pfam (PF00664) Pfam (PF00005) | Cyanidioschyzon merolae strain 10D (Red alga) | |
| 2 | B (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E, F (A) | DECYL-BETA-D-MALTOPYRANOSIDE | non-polymer | 482.6 | 3 | Chemie (DMU) | |||
| 5 | G (A) | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 6 | H (A) | water | water | 18.0 | 435 | Chemie (HOH) |
Sequence modifications
A: 93 - 696 (UniProt: M1VAN7)
| PDB | External Database | Details |
|---|---|---|
| Ala 147 | Gln 147 | engineered mutation |
| Ala 381 | Thr 381 | engineered mutation |
| Gly 697 | - | expression tag |
| Ser 698 | - | expression tag |
| Glu 699 | - | expression tag |
| Asn 700 | - | expression tag |
| Leu 701 | - | expression tag |
| Tyr 702 | - | expression tag |
| Phe 703 | - | expression tag |
| Gln 704 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66046.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2040.2 | |
| All* | Total formula weight | 68086.8 |
