6A33

Binding and Enhanced Binding between Key Immunity Proteins TRAF6 and TIFA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	TNF receptor-associated factor 6	polymer	161	18857.8	1	UniProt (Q9Y4K3) Pfam (PF21355)	Homo sapiens (Human)	E3 ubiquitin-protein ligase TRAF6,Interleukin-1 signal transducer,RING finger protein 85,RING-type E3 ubiquitin transferase TRAF6
2	B (I)	15-mer peptide from TRAF-interacting protein with FHA domain-containing protein A	polymer	15	1614.6	1	UniProt (Q96CG3)	Homo sapiens	Putative MAPK-activating protein PM14,Putative NF-kappa-B-activating protein 20,TRAF2-binding protein
3	C, D (A, I)	water	water		18.0	123	Chemie (HOH)

Sequence modifications

A: 350 - 501 (UniProt: Q9Y4K3)

PDB	External Database	Details
Met 349	-	expression tag
Leu 502	-	expression tag
Glu 503	-	expression tag
His 504	-	expression tag
His 505	-	expression tag
His 506	-	expression tag
His 507	-	expression tag
His 508	-	expression tag
His 509	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	20472.3
All*	Total formula weight	20472.3

*Water molecules are not included.