6A32
Crystal structure of PDGFRA kinase domain mutant T674I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Platelet-derived growth factor receptor alpha | polymer | 356 | 40600.8 | 1 | UniProt (P16234) Pfam (PF07714) In PDB | Homo sapiens (Human) | PDGFR-alpha,Alpha platelet-derived growth factor receptor,Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A,CD140a antigen,Platelet-derived growth factor alpha receptor,Platelet-derived growth factor receptor 2,PDGFR-2 |
| 2 | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A: 550 - 696 (UniProt: P16234)
A: 769 - 973 (UniProt: P16234)
| PDB | External Database | Details |
|---|---|---|
| Gly 546 | - | expression tag |
| Ala 547 | - | expression tag |
| Met 548 | - | expression tag |
| Asp 549 | - | expression tag |
| Ile 674 | Thr 674 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40600.8 | |
| All* | Total formula weight | 40600.8 |
