6A0Z

Crystal structure of broadly neutralizing antibody 13D4 bound to H5N1 influenza hemagglutinin, HA head region

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Hemagglutinin,Envelope glycoprotein	polymer	551	62911.6	1	UniProt (Q45ZR9) UniProt (M1E1E4) Pfam (PF00509) Pfam (PF07921) UniProt (by SIFTS) (Q6DQ34) In PDB	Influenza A virus (A/chicken/Chachoengsao/Thailand/CU-11/04(H5N1))
2	H	Antibody 13D4, Fab Heavy Chain	polymer	224	23888.6	1		Mus musculus
3	L	Antibody 13D4, Fab Light Chain	polymer	214	23630.0	1		Mus musculus
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5		water	water		18.0	299	Chemie (HOH)

Sequence modifications

A: 11 - 507 (UniProt: Q45ZR9)

PDB	External Database	Details
Met 10	-	expression tag
Ser 508	-	linker
Gly 509	-	linker
Arg 510	-	linker
Leu 511	-	linker
Val 512	-	linker
Pro 513	-	linker
Arg 514	-	linker
Gly 515	-	linker
Ser 516	-	linker
Pro 517	-	linker
Gly 518	-	linker
Ser 519	-	linker

A: 520 - 547 (UniProt: M1E1E4)

PDB	External Database	Details
His 548	-	expression tag
His 549	-	expression tag
His 550	-	expression tag
His 551	-	expression tag
His 552	-	expression tag
His 553	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	110430.3
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	110872.7

*Water molecules are not included.