6A06

Structure of pSTING complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Stimulator of interferon genes protein	polymer	201	22833.8	2	UniProt (B8XX90) Pfam (PF15009)	Sus scrofa (Pig)	poSTING,Transmembrane protein 173
2	C, D, E, F (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	G (B)	cGAMP	non-polymer		674.4	1	Chemie (1SY)
4	H, I (A, B)	water	water		18.0	233	Chemie (HOH)

Sequence modifications

A, B: 152 - 342 (UniProt: B8XX90)

PDB	External Database	Details
Ala 150	-	expression tag
Ala 151	-	expression tag
Glu 260	Gly 260	conflict
Leu 343	-	expression tag
Glu 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag
His 348	-	expression tag
His 349	-	expression tag
His 350	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45667.5
Non-Polymers*	Number of molecules	5
	Total formula weight	1058.7
All*	Total formula weight	46726.2

*Water molecules are not included.