6A05

Structure of pSTING complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Stimulator of interferon genes protein	polymer	201	22833.8	2	UniProt (B8XX90) Pfam (PF15009) In PDB	Sus scrofa (Pig)	poSTING,Transmembrane protein 173
2	A, B	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
3	A	2-amino-9-[(2R,3R,3aR,5S,7aS,9R,10R,10aR,12R,14aS)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one	non-polymer		674.4	1	Chemie (1YD)
4		water	water		18.0	37	Chemie (HOH)

Sequence modifications

A, B: 152 - 342 (UniProt: B8XX90)

PDB	External Database	Details
Ala 150	-	expression tag
Ala 151	-	expression tag
Glu 260	Gly 260	conflict
Leu 343	-	expression tag
Glu 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag
His 348	-	expression tag
His 349	-	expression tag
His 350	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45667.5
Non-Polymers*	Number of molecules	4
	Total formula weight	962.6
All*	Total formula weight	46630.1

*Water molecules are not included.