5ZX3
Mycobacterium tuberculosis RNA polymerase holoenzyme with ECF sigma factor sigma H
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DNA-directed RNA polymerase subunit alpha | polymer | 368 | 40279.0 | 2 | UniProt (P9WGZ1) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB | Mycobacterium tuberculosis H37Rv | RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha |
2 | C | DNA-directed RNA polymerase subunit beta | polymer | 1174 | 129602.3 | 1 | UniProt (P9WGY9) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) In PDB | Mycobacterium tuberculosis H37Rv | RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta |
3 | D | DNA-directed RNA polymerase subunit beta' | polymer | 1317 | 147068.1 | 1 | UniProt (P9WGY7) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB | Mycobacterium tuberculosis H37Rv | RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta' |
4 | E | DNA-directed RNA polymerase subunit omega | polymer | 110 | 11851.1 | 1 | UniProt (P9WGY5) Pfam (PF01192) In PDB | Mycobacterium tuberculosis H37Rv | RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega |
5 | F | ECF RNA polymerase sigma factor SigH | polymer | 218 | 24382.2 | 1 | UniProt (P9WGH9) Pfam (PF04542) Pfam (PF08281) In PDB | Mycobacterium tuberculosis H37Rv | ECF sigma factor SigH,Alternative RNA polymerase sigma factor SigH,RNA polymerase sigma-H factor,Sigma-H factor |
6 | D | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
7 | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 347 (UniProt: P9WGZ1)
C: 7 - 1178 (UniProt: P9WGY9)
D: 2 - 1316 (UniProt: P9WGY7)
F: 1 - 216 (UniProt: P9WGH9)
PDB | External Database | Details |
---|---|---|
Met -20 | - | expression tag |
Gly -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Ser -8 | - | expression tag |
Ser -7 | - | expression tag |
Gly -6 | - | expression tag |
His -5 | - | expression tag |
Ile -4 | - | expression tag |
Glu -3 | - | expression tag |
Gly -2 | - | expression tag |
Arg -1 | - | expression tag |
His 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 5 | - | expression tag |
Val 6 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 0 | - | expression tag |
Val 1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 393461.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 393592.7 |