5ZWK

Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with fructose-1,6-bisphophate and AMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Fructose-1,6-bisphosphatase 1	polymer	348	38206.8	4	UniProt (Q2TU34) Pfam (PF00316) Pfam (PF18913)	Homo sapiens (Human)	Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA
2	E, I, M, Q (A, B, C, D)	1,6-di-O-phosphono-beta-D-fructofuranose	non-polymer		340.1	4	Chemie (FBP)
3	F, J, N, R (A, B, C, D)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	4	Chemie (AMP)
4	G, H, K, L, O... (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)
5	U, V, W, X (A, B, C, D)	water	water		18.0	433	Chemie (HOH)

Sequence modifications

A, B, C, D: 0 - 337 (UniProt: Q2TU34)

PDB	External Database	Details
Leu 338	-	expression tag
Glu 339	-	expression tag
His 340	-	expression tag
His 341	-	expression tag
His 342	-	expression tag
His 343	-	expression tag
His 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	152827.4
Non-Polymers*	Number of molecules	16
	Total formula weight	2943.8
All*	Total formula weight	155771.2

*Water molecules are not included.