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5ZQP

Tankyrase-2 in complex with compound 12

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATankyrase-2polymer16819150.61UniProt (Q9H2K2)
Pfam (PF00644)
In PDB
Homo sapiens (Human)TANK2,ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-like protein,Tankyrase-related protein
2BTankyrase-2polymer485364.01UniProt (Q9H2K2)
In PDB
Homo sapiens (Human)TANK2,ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-like protein,Tankyrase-related protein
3AZINC IONnon-polymer65.41Chemie (ZN)
4A1'-(4-oxo-3,4,5,6,7,8-hexahydroquinazolin-2-yl)-2H-spiro[1-benzofuran-3,4'-piperidin]-2-onenon-polymer351.41Chemie (9H3)
5APHOSPHATE IONnon-polymer95.01Chemie (PO4)
6A, BGLYCEROLnon-polymer92.12Chemie (GOL)
7waterwater18.0114Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight24514.7
Non-Polymers*Number of molecules5
Total formula weight696.0
All*Total formula weight25210.6
*Water molecules are not included.

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PDB entries from 2024-05-01

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