5ZQG
Complex structure of PEDV 3CLpro mutant (C144A) with NEMO-231 peptite substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Non-structural protein | polymer | 308 | 33637.0 | 2 | UniProt (R4JK63) | Porcine epidemic diarrhea virus | 3CLpro |
| 2 | C (C) | PEPTIDE LEU-ALA-GLN-LEU-GLN-VAL-ALA | polymer | 11 | 1300.5 | 1 | Sus scrofa | ||
| 3 | D, E, F (A, B, C) | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 299 (UniProt: R4JK63)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Ala 144 | Cys 3141 | engineered mutation |
| Leu 300 | - | expression tag |
| Glu 301 | - | expression tag |
| His 302 | - | expression tag |
| His 303 | - | expression tag |
| His 304 | - | expression tag |
| His 305 | - | expression tag |
| His 306 | - | expression tag |
| His 307 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 68574.6 | |
| All* | Total formula weight | 68574.6 |
