5ZOP
Crystal structure of histone deacetylase 4 (HDAC4) in complex with a SMRT corepressor SP2 fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | Histone deacetylase 4 | polymer | 399 | 42998.8 | 1 | UniProt (P56524) Pfam (PF00850) | Homo sapiens (Human) | HD4 |
| 2 | B (A) | SMRT corepressor SP2 fragment | polymer | 12 | 1294.4 | 1 | UniProt (by SIFTS) (Q9Y618) | Homo sapiens | |
| 3 | C, D (G) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 4 | E, F (G) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | G, H (G, A) | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
G: 652 - 1050 (UniProt: P56524)
| PDB | External Database | Details |
|---|---|---|
| Tyr 976 | His 976 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44293.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 209.0 | |
| All* | Total formula weight | 44502.2 |
