5ZOK

Crystal structure of human SMAD1-MAN1 complex.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Mothers against decapentaplegic homolog 1	polymer	209	23650.6	2	UniProt (Q15797) Pfam (PF03166)	Homo sapiens (Human)	Mothers against DPP homolog 1,JV4-1,Mad-related protein 1,SMAD family member 1,hSMAD1,Transforming growth factor-beta-signaling protein 1,BSP-1
2	B, D (B, D)	Inner nuclear membrane protein Man1	polymer	132	14970.2	2	UniProt (Q9Y2U8)	Homo sapiens (Human)	LEM domain-containing protein 3

Sequence modifications

A, C: 259 - 462 (UniProt: Q15797)

PDB	External Database	Details
Gly 257	-	expression tag
Pro 258	-	expression tag
Glu 463	-	expression tag
Val 464	-	expression tag
Glu 465	-	expression tag

B, D: 762 - 890 (UniProt: Q9Y2U8)

PDB	External Database	Details
Gly 759	-	expression tag
Pro 760	-	expression tag
Gly 761	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	77241.4
All*	Total formula weight	77241.4

*Water molecules are not included.