5ZMW
Crystal structure of the E309Q mutant of SR Ca2+-ATPase in E2(TG)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | polymer | 1000 | 110173.2 | 1 | UniProt (P04191) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00702) Pfam (PF00689) | Oryctolagus cuniculus (Rabbit) | SR Ca(2+)-ATPase 1,Calcium pump 1,Calcium-transporting ATPase sarcoplasmic reticulum type,fast twitch skeletal muscle isoform,Endoplasmic reticulum class 1/2 Ca(2+) ATPase |
| 2 | B (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER | non-polymer | 650.8 | 1 | Chemie (TG1) | |||
| 5 | E, F (A) | DECYL-BETA-D-MALTOPYRANOSIDE | non-polymer | 482.6 | 2 | Chemie (DMU) | |||
| 6 | G (A) | water | water | 18.0 | 236 | Chemie (HOH) |
Sequence modifications
A: 1 - 994 (UniProt: P04191)
| PDB | External Database | Details |
|---|---|---|
| Ser -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asn -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Ile -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Gln 309 | Glu 309 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 110173.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1734.9 | |
| All* | Total formula weight | 111908.1 |
