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5ZMV

Crystal structure of the E309A mutant of SR Ca2+-ATPase in E2(TG)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASarcoplasmic/endoplasmic reticulum calcium ATPase 1polymer1000110116.11UniProt (P04191)
Pfam (PF00690)
Pfam (PF00122)
Pfam (PF13246)
Pfam (PF00702)
Pfam (PF00689)
In PDB
Oryctolagus cuniculus (Rabbit)SR Ca(2+)-ATPase 1,Calcium pump 1,Calcium-transporting ATPase sarcoplasmic reticulum type,fast twitch skeletal muscle isoform,Endoplasmic reticulum class 1/2 Ca(2+) ATPase
2ASULFATE IONnon-polymer96.12Chemie (SO4)
3ASODIUM IONnon-polymer23.01Chemie (NA)
4AOCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OXY]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTERnon-polymer650.81Chemie (TG1)
5APHOSPHATIDYLETHANOLAMINEnon-polymer734.03Chemie (PTY)
Sequence modifications
A: 1 - 994 (UniProt: P04191)
PDBExternal DatabaseDetails
Ser -5-expression tag
Asp -4-expression tag
Asn -3-expression tag
Ala -2-expression tag
Ile -1-expression tag
Ala 0-expression tag
Ala 309Glu 309engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight110116.1
Non-Polymers*Number of molecules7
Total formula weight3068.0
All*Total formula weight113184.1
*Water molecules are not included.

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PDB entries from 2024-06-12

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