5ZMA
Structural basis for an allosteric Eya2 phosphatase inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, A, C) | Eyes absent homolog 2 | polymer | 294 | 33026.3 | 3 | UniProt (O00167) Pfam (PF00702) | Homo sapiens (Human) | |
| 2 | D, E, F (B, A, C) | 3-fluoro-N'-[(E)-{5-[(pyrimidin-2-yl)sulfanyl]furan-2-yl}methylidene]benzohydrazide | non-polymer | 342.3 | 3 | Chemie (9FX) |
Sequence modifications
B, A, C: 253 - 538 (UniProt: O00167)
| PDB | External Database | Details |
|---|---|---|
| Gly 245 | - | expression tag |
| Pro 246 | - | expression tag |
| Leu 247 | - | expression tag |
| Gly 248 | - | expression tag |
| Ser 249 | - | expression tag |
| Pro 250 | - | expression tag |
| Glu 251 | - | expression tag |
| Phe 252 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 99079.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1027.0 | |
| All* | Total formula weight | 100106.1 |
