5ZK8

Crystal structure of M2 muscarinic acetylcholine receptor bound with NMS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Muscarinic acetylcholine receptor M2,Redesigned apo-cytochrome b562,Muscarinic acetylcholine receptor M2	polymer	421	47223.1	1	UniProt (P08172) Pfam (PF00001) Pfam (PF07361) UniProt (by SIFTS) (P0ABE7)	Homo sapiens (Human)
2	B (A)	N-methyl scopolamine	non-polymer		318.4	1	Chemie (3C0)
3	C (A)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A: 10 - 217 (UniProt: P08172)

PDB	External Database	Details
Gly -1	-	expression tag
Pro 0	-	expression tag
Met 1	-	expression tag
Asp 2	-	expression tag
Asp 3	-	expression tag
Ser 4	-	expression tag
Thr 5	-	expression tag
Asp 6	-	expression tag
Ser 7	-	expression tag
Ser 8	-	expression tag
Asp 9	-	expression tag

A: 1001 - 1106 (PDB: 5ZK8)
A: 377 - 466 (UniProt: P08172)

PDB	External Database	Details
Leu 467	-	expression tag
Glu 468	-	expression tag
Val 469	-	expression tag
Leu 470	-	expression tag
Phe 471	-	expression tag
Gln 472	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	47223.1
Non-Polymers*	Number of molecules	1
	Total formula weight	318.4
All*	Total formula weight	47541.5

*Water molecules are not included.