5ZJY
Stapled-peptides tailored against initiation of translation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Eukaryotic translation initiation factor 4E | polymer | 191 | 22290.3 | 1 | UniProt (P06730) Pfam (PF01652) | Homo sapiens (Human) | eIF4E,eIF-4F 25 kDa subunit |
| 2 | B (B) | LYS-LYS-ARG-TYR-SER-ARG-2JN-GLN-LEU-LEU-2JN-PHE | polymer | 14 | 1621.0 | 1 | Homo sapiens | ||
| 3 | C (A) | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 538.2 | 1 | Chemie (MGP) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A: 28 - 217 (UniProt: P06730)
| PDB | External Database | Details |
|---|---|---|
| Met 27 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23911.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 538.2 | |
| All* | Total formula weight | 24449.6 |
