5ZID
Crystal Structure of human DPP-IV in complex with HL2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dipeptidyl peptidase 4 | polymer | 734 | 85261.5 | 2 | UniProt (P27487) Pfam (PF00930) Pfam (PF00326) | Homo sapiens (Human) | ADABP,Adenosine deaminase complexing protein 2,ADCP-2,Dipeptidyl peptidase IV,DPP IV,T-cell activation antigen CD26,TP103 |
| 2 | C (C) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 707.6 | 1 | In PDB GlyTouCan (G99218JM) | |||
| 3 | D, F (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | E, G (A, B) | (2S,3R)-2-amino-9-methoxy-3-(2,4,5-trifluorophenyl)-2,3-dihydro-1H-naphtho[2,1-b]pyran-8-carbonitrile | non-polymer | 384.4 | 2 | Chemie (9EL) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A, B: 40 - 766 (UniProt: P27487)
| PDB | External Database | Details |
|---|---|---|
| Gly 767 | - | expression tag |
| His 768 | - | expression tag |
| His 769 | - | expression tag |
| His 770 | - | expression tag |
| His 771 | - | expression tag |
| His 772 | - | expression tag |
| His 773 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 170523.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 707.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1211.1 | |
| All* | Total formula weight | 172441.7 |
