5ZEF

Crystal structure of Entamoeba histolytica Arginase in complex with L- Norvaline at 2.01 A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Arginase	polymer	312	34826.9	2	UniProt (C4LSS0) Pfam (PF00491)	Entamoeba histolytica
2	C, I (A, B)	NORVALINE	non-polymer		117.1	2	Chemie (NVA)
3	D, E, J, K (A, B)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)
4	F, G (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	H, L (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6	M, N (A, B)	water	water		18.0	292	Chemie (HOH)

Sequence modifications

A, B: 1 - 296 (UniProt: C4LSS0)

PDB	External Database	Details
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69653.8
Non-Polymers*	Number of molecules	10
	Total formula weight	762.4
All*	Total formula weight	70416.2

*Water molecules are not included.