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5ZE0

Hairpin Forming Complex, RAG1/2-Nicked(with Dideoxy) 12RSS/23RSS complex in Mg2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
mouse RAG1polymer62771871.32UniProt (P15919)
Pfam (PF12940)
Mus musculus (Mouse)RAG-1
2B, D
(B, D)
mouse RAG2polymer38943225.72UniProt (P21784)
Pfam (PF03089)
Mus musculus (Mouse)RAG-2
3E
(N)
HMGB1 A-B boxpolymer16318897.91UniProt (P63158)
Pfam (PF09011)
Pfam (PF00505)
Mus musculus (Mouse)High mobility group protein 1,HMG-1
4F
(F)
DNA (45-MER)polymer4513979.01synthetic construct
5G
(I)
DNA (5'-D(*AP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3')polymer164864.21synthetic construct
6H
(J)
DNA (5'-D(*TP*AP*TP*CP*TP*GP*GP*CP*CP*TP*GP*TP*CP*TP*TP*A)-3')polymer164855.11synthetic construct
7I
(G)
DNA (54-MER)polymer5416640.71synthetic construct
8J
(L)
DNA (30-MER)polymer309138.91synthetic construct
9K
(M)
DNA (39-MER)polymer3912036.81synthetic construct
10L, Q
(A, C)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
11M, R
(A, C)
ZINC IONnon-polymer65.42Chemie (ZN)
12N, O, T
(A, C)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
13P, S
(A, C)
POTASSIUM IONnon-polymer39.12Chemie (K)
14AA, BA, CA, DA, U...
(J, G, L, M, A...)
waterwater18.0169Chemie (HOH)
Sequence modifications
A, C: 384 - 1008 (UniProt: P15919)
PDBExternal DatabaseDetails
Gly 382-cloning artifact
Pro 383-cloning artifact
B, D: 1 - 387 (UniProt: P21784)
PDBExternal DatabaseDetails
Gly -1-cloning artifact
Pro 0-cloning artifact
Val 1Met 1engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains11
Total formula weight310606.6
Non-Polymers*Number of molecules9
Total formula weight443.8
All*Total formula weight311050.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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