5ZCM

Crystal structure of Xylose reductase from Debaryomyces nepalensis in complex with NADP-DTT adduct

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Aldose reductase	polymer	341	38920.3	1	UniProt (A0A0M4HL56)	Debaryomyces nepalensis
2	B (A)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	1	Chemie (NDP)
3	C (A)	2,3-DIHYDROXY-1,4-DITHIOBUTANE	non-polymer		154.3	1	Chemie (DTT)
4	D (A)	water	water		18.0	308	Chemie (HOH)

Sequence modifications

A: 1 - 320 (UniProt: A0A0M4HL56)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	38920.3
Non-Polymers*	Number of molecules	2
	Total formula weight	899.7
All*	Total formula weight	39820.0

*Water molecules are not included.