5ZBX

The crystal structure of the nucleosome containing histone H3.1 CATD(V76Q, K77D)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Histone H3.1,Histone H3-like centromeric protein A,Histone H3.1	polymer	141	16078.8	2	UniProt (P68431) UniProt (P49450) Pfam (PF00125)	Homo sapiens (Human)	Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l,Centromere autoantigen A,Centromere protein A,CENP-A
2	B, F (B, F)	Histone H4	polymer	106	11676.7	2	UniProt (P62805) Pfam (PF15511)	Homo sapiens (Human)
3	C, G (C, G)	Histone H2A type 1-B/E	polymer	133	14447.8	2	UniProt (P04908) Pfam (PF00125) Pfam (PF16211)	Homo sapiens (Human)	Histone H2A.2,Histone H2A/a,Histone H2A/m
4	D, H (D, H)	Histone H2B type 1-J	polymer	129	14217.5	2	UniProt (P06899) Pfam (PF00125)	Homo sapiens (Human)	Histone H2B.1,Histone H2B.r,H2B/r
5	I, J (I, J)	DNA (146-MER)	polymer	146	45053.9	2		Homo sapiens
6	K, M (C, G)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
7	L, N, O, P, Q... (E, I, J)	MANGANESE (II) ION	non-polymer		54.9	8	Chemie (MN)
8	U, V (E, F)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A, E: 0 - 74 (UniProt: P68431)

A, E: 75 - 114 (UniProt: P49450)

PDB	External Database	Details
Gln 76	Val 76	engineered mutation
Asp 77	Lys 77	engineered mutation

A, E: 115 - 137 (UniProt: P68431)
B, F: 0 - 102 (UniProt: P62805)

C, G: 0 - 129 (UniProt: P04908)

D, H: 0 - 125 (UniProt: P06899)

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.