5ZAN
Crystal Structure of Aurora-A in complex with a new Quinazoline inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aurora kinase A | polymer | 281 | 32560.3 | 1 | UniProt (O14965) Pfam (PF00069) | Homo sapiens (Human) | Aurora 2,Aurora/IPL1-related kinase 1,hARK1,Breast tumor-amplified kinase,Serine/threonine-protein kinase 15,Serine/threonine-protein kinase 6,Serine/threonine-protein kinase aurora-A |
| 2 | B (A) | 7-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]quinazolin-4-amine | non-polymer | 425.5 | 1 | Chemie (9A6) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32560.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 425.5 | |
| All* | Total formula weight | 32985.9 |
