5ZAM
Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Endoribonuclease Dicer | polymer | 1922 | 218947.3 | 1 | UniProt (Q9UPY3) Pfam (PF00270) Pfam (PF20930) Pfam (PF00271) Pfam (PF03368) Pfam (PF20931) Pfam (PF02170) Pfam (PF00636) Pfam (PF20932) In PDB | Homo sapiens (Human) | Helicase with RNase motif,Helicase MOI |
| 2 | B | RISC-loading complex subunit TARBP2 | polymer | 366 | 39085.3 | 1 | UniProt (Q15633) Pfam (PF00035) In PDB | Homo sapiens (Human) | TRBP, TAR RNA-binding protein 2,Trans-activation-responsive RNA-binding protein |
| 3 | C | RNA (73-mer) | polymer | 73 | 23375.8 | 1 | Homo sapiens (Human) | Prelet7 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 281408.4 | |
| All* | Total formula weight | 281408.4 |
