5Z8K

Crystal structure of an aminotransferase in complex with product-1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	C-6' aminotransferase	polymer	437	47174.4	2	UniProt (Q70KD9)	Micromonospora echinospora (Micromonospora purpurea)	Gentamicin (Hexosaminyl-6-) aminotransferase I,GntW,Putative glutamate-1-semialdehyde aminotransferase
2	C, E (A, B)	PYRIDOXAL-5'-PHOSPHATE	non-polymer		247.1	2	Chemie (PLP)
3	D, F (A, B)	(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside	non-polymer		322.4	2	Chemie (XXX)
4	G, H (A, B)	water	water		18.0	626	Chemie (HOH)

Sequence modifications

A, B: 1 - 417 (UniProt: Q70KD9)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	94348.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1139.0
All*	Total formula weight	95487.8

*Water molecules are not included.