5Z6L
High-pressure Crystal Structure Analysis of M20 loop closed DHFR at 650 MPa
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dihydrofolate reductase | polymer | 162 | 18377.7 | 1 | UniProt (P0ABQ4) Pfam (PF00186) In PDB | Escherichia coli (strain K12) | |
2 | A | FOLIC ACID | non-polymer | 441.4 | 1 | Chemie (FOL) | |||
3 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
4 | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ4)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 18377.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1184.8 | |
All* | Total formula weight | 19562.5 |