5Z5V
The first bromodomain of BRD4 with compound BDF-1253
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bromodomain-containing protein 4 | polymer | 125 | 14883.2 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
2 | A | N-{8-hydroxy-4-[(1H-imidazol-1-yl)methyl]quinolin-2-yl}acetamide | non-polymer | 282.3 | 1 | Chemie (96X) | |||
3 | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A: 44 - 167 (UniProt: O60885)
PDB | External Database | Details |
---|---|---|
Met 43 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 14883.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 282.3 | |
All* | Total formula weight | 15165.5 |