5Z5U
The first bromodomain of BRD4 with compound BDF-2254
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 4 | polymer | 125 | 14883.2 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
| 2 | A | 2-amino-4-(1H-imidazol-1-yl)quinoline-6,8-diol | non-polymer | 242.2 | 1 | Chemie (96U) | |||
| 3 | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
A: 44 - 167 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14883.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 242.2 | |
| All* | Total formula weight | 15125.4 |
