5Z2R
ThDP-Mn2+ complex of R395K variant of EcMenD soaked with 2-ketoglutarate for 5 min
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | polymer | 556 | 61405.8 | 8 | UniProt (P17109) Pfam (PF02776) Pfam (PF16582) Pfam (PF02775) | Escherichia coli (strain K12) | SEPHCHC synthase,Menaquinone biosynthesis protein MenD |
| 2 | AB, I, N, OA, R... (H, A, B, F, C...) | (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid | non-polymer | 527.4 | 7 | Chemie (TD6) | |||
| 3 | BB, GA, J, O, PA... (H, E, A, B, F...) | MAGNESIUM ION | non-polymer | 24.3 | 7 | Chemie (MG) | |||
| 4 | AA, BA, CA, CB, DA... (D, H, E, A, B...) | FORMIC ACID | non-polymer | 46.0 | 29 | Chemie (FMT) | |||
| 5 | M, NA (A, E) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | MA (E) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 1 | Chemie (TPP) | |||
| 7 | VA (G) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 8 | DB, EB, FB, GB, HB... (A, B, C, D, E...) | water | water | 18.0 | 3190 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 556 (UniProt: P17109)
| PDB | External Database | Details |
|---|---|---|
| Lys 395 | Arg 395 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 491246.1 | |
| Non-Polymers* | Number of molecules | 47 |
| Total formula weight | 5861.1 | |
| All* | Total formula weight | 497107.2 |
