5Z2P
ThDP-Mn2+ complex of R413K variant of EcMenD soaked with 2-ketoglutarate for 5 min
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | polymer | 556 | 61405.8 | 8 | UniProt (P17109) Pfam (PF02776) Pfam (PF16582) Pfam (PF02775) | Escherichia coli (strain K12) | SEPHCHC synthase,Menaquinone biosynthesis protein MenD |
| 2 | CA, HA, I, PA, Q... (E, F, A, G, B...) | (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid | non-polymer | 527.4 | 8 | Chemie (TD6) | |||
| 3 | DA, IA, J, QA, R... (E, F, A, G, B...) | MANGANESE (II) ION | non-polymer | 54.9 | 8 | Chemie (MN) | |||
| 4 | AA, EA, FA, GA, JA... (D, E, F, A, G...) | FORMIC ACID | non-polymer | 46.0 | 23 | Chemie (FMT) | |||
| 5 | BA, TA (D, G) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | AB, BB, CB, DB, EB... (D, E, F, G, H...) | water | water | 18.0 | 2516 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 556 (UniProt: P17109)
| PDB | External Database | Details |
|---|---|---|
| Lys 413 | Arg 413 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 491246.1 | |
| Non-Polymers* | Number of molecules | 41 |
| Total formula weight | 5901.5 | |
| All* | Total formula weight | 497147.6 |
